CASE STUDY:
Pellucid Marginal Degeneration / Keratoconus
 
   
    This case study illustrates how Biometric Scleral LensesTM addressed a specific patient's vision problems due to Pellucid Marginal Degeneration and Keratoconus.

 
   

The patient is a 26-year old man with a history of keratoconus.

  • Manifest refraction
  • OD:-2.50 -3.50 x 100 20/25
  • OS:-2.75 -4.50 x 097 20/30

Pellucid marginal degeneration is similar to the other corneal thinning disorder, keratoconus. Patients typically develop high irregular astigmatism that cannot be fully corrected with eyeglasses or soft contact lenses.

 
 
Corneal Topography
         
  Irregular asitigmatism visualized through corneal tomography   Corneal topography shows the large inferior area of steepening and the central bowtie pattern of irregular astigmatism.
 
  OCT Pachymetry    
Optical coherence tomography reveals areaa of corneal thinning  

Optical Coherence Pachymetry plots a map of corneal thickness. The hotter colors indicate thinning. In this case, the thinning corresponds to the location of the corneal steepening evident on the corneal topography.

 

 

  OCT Scan Axis 180    
 
Optical Coherence Tomography of high astigmatism
  An OCT scan through the central cornea in the horizontal meridian appears normal and symmetrical.
  CT Scan Axis 90
   
 
OCT scan demonstrated irregular astigmatism
  When the OCT scan is taken through the steep section of the cornea, the steeper area can be readily appreciated. The lower cornea is on the left, and the upper cornea is on the right. Notice how much flatter the upper cornea is compared to the lower cornea.
 
Retinal Spot Diagram
   
 
Irregular astigmatism makes it difficult to focus light
  The result is that light is not focused inside the eye.
 
HOA Point Spread Function
     
 
A smeared image demonstrates problems focusing light
  Even with glasses, this is how a point source of light might appear in dim light. The extent of the smeared image is quite large.  
 
Start of Design Process
     
 
Scleral lens design begins on patient with high, irregular astigmatism
 

Design of the lens begins as detailed measurements are taken of the cornea and sclera.

 
 
Scleral Lens Apical Clearance
   
 
Scleral lens fits comfortably
 

The result is a lens that is very comfortable and clears the corneal apex.

 
 
Fluorescein Pattern
     
  Thinning of cornea visible under alternative light  

The fluorescein pattern reveals the thicker and thinner areas of the tear film between the lens and the cornea. The tear film is thinnest in the area of the apex.

 

 
 
Retinal Spot Diagram with Lens
   
 
Scleral lens design allows for more accurate focus of light
 

The final lens design was a quadrant specific design with different lens powers within the optical zone. The net result is a significant tightening of the retinal image and a significant decrease in higher order aberrations from 1.471 microns to 0.568 microns.

 

 
 
Point Spread Function with Lens
   
  Scleral lenses focus pinpoint of light accurately  

The lens makes the point source of light look like a point source of light.

 
                 
 


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